TRIMETREXATE MONOHYDRATE, MONOACETATE
\tɹˈa͡ɪmiːtəksˌe͡ɪt mˈɒnə͡ʊhˌa͡ɪdɹe͡ɪt], \tɹˈaɪmiːtəksˌeɪt mˈɒnəʊhˌaɪdɹeɪt], \t_ɹ_ˈaɪ_m_iː_t_ə_k_s_ˌeɪ_t m_ˈɒ_n_əʊ_h_ˌaɪ_d_ɹ_eɪ_t]\
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A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against Pneumocystis carinii pneumonia in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
By DataStellar Co., Ltd
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
Nearby Words
- trimethylxanthine
- trimetin
- trimetoquinol
- trimetrexate
- trimetrexate hydrate
- Trimetrexate Monohydrate, Monoacetate
- trimetric
- trimetrical
- trimetrio system
- trimezole
- trimipramine