VARIAMENTO

\vˌe͡əɹi͡əmˈɛntə͡ʊ], \vˌe‍əɹi‍əmˈɛntə‍ʊ], \v_ˌeə_ɹ_iə_m_ˈɛ_n_t_əʊ]\

Definitions of VARIAMENTO

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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