ZIMELDINE HYDROCHLORIDE
\zˈa͡ɪmldiːn hˈa͡ɪdɹəklˌɔːɹa͡ɪd], \zˈaɪmldiːn hˈaɪdɹəklˌɔːɹaɪd], \z_ˈaɪ_m_l_d_iː_n h_ˈaɪ_d_ɹ_ə_k_l_ˌɔː_ɹ_aɪ_d]\
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One of the SEROTONIN UPTAKE INHIBITORS formerly used for depression but was withdrawn worldwide in September 1983 because of the risk of GUILLAIN-BARRE SYNDROME associated with its use. (From Martindale, The Extra Pharmacopoeia, 29th ed, p385)
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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