COALTAR CREOSOTE

\kˈə͡ʊltə kɹɪˈɒsə͡ʊt], \kˈə‍ʊltə kɹɪˈɒsə‍ʊt], \k_ˈəʊ_l_t_ə k_ɹ_ɪ__ˈɒ_s_əʊ_t]\

Definitions of COALTAR CREOSOTE

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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