MARCELLUS EMANTS

\mˈɑːsɛləs ɪmˈants], \mˈɑːsɛləs ɪmˈants], \m_ˈɑː_s_ɛ_l_ə_s ɪ_m_ˈa_n_t_s]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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