SPARTIUM SCOPARIUM

\spˈɑːti͡əm skəpˈe͡əɹi͡əm], \spˈɑːti‍əm skəpˈe‍əɹi‍əm], \s_p_ˈɑː_t_iə_m s_k_ə_p_ˈeə_ɹ_iə_m]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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